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Expires On
June 15, 2021
The recent literature shows an increase of breast cancer in women under 50, however still few are the studies which analyse the impact of the disease in this specific target age. This study aims at exploring the most prevalent topics in Italian cancer blogs of women who have received a breast cancer diagnosis before the age of 50, in order to understand their experience of illness and the. Purpose: The purpose of this qualitative study was to examine patient opinions about anxiety in cancer survivorship, particularly the role of the primary care provider in management of anxiety related to the trajectory of long-term cancer survivorship. Methods: Respondents to a mass email (N = 22,000) were invited to participate in 1 of 3 institutional review board-approved focus group meetings. Wanted to know what features Astro Gold has yet to implement that are already on Solar Fire? Is it worth the hassle to instead Solar Fire on the Mac or Astro Gold has enough of essential features to just install it since it's available for Mac Users? In going through the macOS computer setup instructions in the biostar handbook, the XCode version in the App Store requires macOS version 10.15.2 or later.
Completion Time
150 minutes
Topic(s)
Oncology
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This activity is jointly provided by Amedco LLC and CancerNet LLC.
This activity is supported in part by an independent education grant from Bristol-Myers Squibb, Merck Sharp & Dohme Corp. and Eisai, Inc.
Credit Available
- Physicians, Physicians Assistants, Nurse Practitioners — maximum of 2.5 AMA PRA Category 1 Credit(s)™
- Nurses — Maximum of 2.5 CNE Contact Hours
- Pharmacists — Maximum of 2.5 contact hours (0.25 CEUs) knowledge-based credits
All other health care professionals completing this course will be issued a statement of participation.
Target Audience
This activity is designed to meet the educational needs of medical oncologists, urologists, radiation oncologists, nurse practitioners, physician assistants, nurses, pharmacists on the latest advances in the diagnosis, and treatment of genitourinary cancers (prostate cancer, renal cell carcinoma and urothelial carcinoma). Free slots download for pc. Interactable project mac os.
Program Overview
This enduring webcast will cover topics on the diagnosis, treatment, and management of patients with genitourinary cancers (prostate cancer, renal cell carcinoma and urothelial carcinoma).
Learning Objectives
Upon completion of this activity, participants should be better able to:
- Appraise the efficacy and safety of novel combinations of ADT and androgen axis inhibitors in patients with prostate cancer
- Assess sequential treatment strategies and combination therapies for renal cell carcinoma (RCC) with multitargeted kinase inhibitors
- Evaluate immunotherapy options with PD-1/PD-L1 checkpoint inhibitors and targeted therapy combinations in the treatment of RCC
- Outline the immunotherapy and antibody-drug conjugate based therapies for urothelial carcinoma
Faculty
Nizar M. Tannir, MD
Professor and Chair ad interim, Ransom Horne, Jr. Professor in Cancer Research, Department of Genitourinary Medical Oncology, Division of Cancer Medicine, UT MD Anderson Cancer Center, Houston, TX
Robert Motzer, MD
Attending Physician, Memorial Sloan-Kettering Cancer Center, Professor of Medicine, Weill Medical College of Cornell University, New York, NY
Amado J Zurita, MD
Associate Professor of Medicine, MD Anderson Cancer Center, Department of Genitourinary Medical Oncology | Division of Cancer Medicine, Houston, TX
Joaquim Bellmunt, MD, PhD
Director, Bladder Cancer Program, Beth Israel Deaconess Medical Center, Associate Professor of Medicine, Harvard Medical School, Boston, MA
Accreditation Statement
In support of improving patient care, this activity has been planned and implemented by Amedco LLC and CancerNet, LLC. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation
AMA PRA Category 1 Credit(s)™
Amedco designates this enduring material for a maximum of 2.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing and Pharmacist Continuing Education
Amedco LLC designates this enduring activity for a maximum of 2.50 contact hours for nurses and 2.50 knowledge-based contact hours for pharmacists. Learners should claim only the credit commensurate with the extent of their participation in the activity. Event UAN: JA4008163-9999-20-043-L04-P.
Disclosures of Conflicts of Interest
Joaquim Bellmunt, MD, PhD
- Consultant: Genentech, Merck, Pfizer, GSK, BMS, Pierre-Fabre, Sanofi Aventis, Astellas, OncoGenex, Janssen
- Speaker: Pfizer, Merck, GSK, Novartis, Pierre-Fabre, Astellas
- Research Funding: Takeda, Pfizer, Novartis, Sanofi-Aventis
Robert Motzer, MD
- Consultant: Pfizer, Merck, Genentech Roche
- Research Funding: BMS, Eisai, Exelixis
Island of captivity mac os. Nizar M. Tannir, MD Negative world mac os.
- Consultant: Bristol-Myers Squibb, Calithera Bioscience, Eisai Medical Research, Exelixis Inc., Ipsen, Nektar Therapeutics, Novartis, ONO Pharmaceutical, Pfizer Inc., Neoleukin Therapeutics, Merck, Surface Oncology, Lilly
- Research Funding Bristol-Myers Squibb, Calithera Bioscience, Exelixis Inc., Epizyme, Nektar Therapeutics, Novartis, Mirati Therapeutics, Pfizer Inc., Takeda Pharmaceutical Company Ltd., Arrowhead
Amado J Zurita, MD
- Consultant: Janssen, Exelixis, Bayer
- Research Funding:Pfizer, X4 Pharma, Infinity Pharma
Planners and Managers Disclosures
The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME webcast:
- Kamatham A. Naidu, PhD (CancerNet, LLC), has no relevant financial relationships.
- Brian Waggoner (CancerNet, LLC) has no relevant financial relationships to disclose.
- Sheryl Morgan (Amedco) has no relevant financial relationships to disclose.
Instructions for Participation and Credit
Generic instructions are part of the site, but you may wish to include specific instructions such as the following. Participation in this activity is free. Understand the material, pass the intra-activity questions and complete an evaluation to receive credit. Passing grade is 70% and you are limited to 5 attempts.
There are no fees for participating and receiving CME credit for this enduring activity. To receive CME credit participants must:
- Read the CME/CE information and faculty disclosures.
- Participate in the online activity.
- Submit the evaluation form to the Med Learning Group.
Course Viewing Requirements
Generic instructions are part of the site, but you may wish to include specific instructions such as the following. Participation in this activity is free. Understand the material, pass the intra-activity questions and complete an evaluation to receive credit. Passing grade is 70% and you are limited to 5 attempts.
There are no fees for participating and receiving CME credit for this enduring activity. To receive CME credit participants must:
- Read the CME/CE information and faculty disclosures.
- Participate in the online activity.
- Submit the evaluation form to the Med Learning Group.
Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above
Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
Disclosure of Unlabeled Use
Amedco and CancerNet require that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.
Disclaimer
Amedco makes every effort to develop CME activities that are scientifically based.
This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.
Contact Information
For CME questions, please contact: Amedco at: certificate@amedcoemail.com
Contact this CME provider at Amedco for privacy and confidentiality policy statement information at: Sheryl@amedcoemail.com
The Gallo laboratory is interested in the understanding and therapeutic targeting of signaling pathways that govern cancer progression. In particular, we have focused on the mixed-lineage kinase (MLK) family (Figure 1) and their roles in cancer invasion and metastasis, particularly in the context of breast cancer. We have demonstrated a critical role for MLK3 in triple-negative breast cancer metastasis (Figure 2), in regulating both focal adhesion turnover during cell migration and gene expression during invasion and metastasis. In addition we are studying the roles of MLK family members and related signaling in lung cancer, glioblastoma, and melanoma.
Vinnie Cancer Mac Os Download
Triple-negative breast cancers (TNBCs) have high rates of metastasis and early metastatic recurrence and lack targeted therapies. During cancer metastasis, individual or small groups of tumor cells must break away from the primary tumor, invade through extracellular matrix, intravasate through the endothelial layer of the vasculature to enter the bloodstream. Subpopulations of these 'circulating tumor cells' are responsible for metastatic colonization. We are studying the molecular characteristics of circulating tumor cells derived from a TNBC model, including their gene expression and signaling pathways, with the aim of identifying important druggable targets to combat breast cancer metastasis.
Estrogen receptor-positive (ER+) breast tumors are typically less aggressive than TNBCs and often respond to endocrine therapies, but endocrine resistance and late metastatic recurrence are major causes of mortality in these women. Late metastatic recurrence is thought to occur upon reacativation of dormant tumor cells that have disseminated to distant organs. We are investigating pathways responsible for reactivation of dormant tumor cells, in order to identify appropriate drug targets.
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Figure 2. MLK3 signaling in triple-negative breast cancer.
Vinnie Cancer Mac Os X
Our laboratory uses diverse approaches and techniques to study mechanisms of tumor proliferation, invasion and metastatic outgrowth including 3D organotypic assays, cell biology, animal models, mass spectrometry, and biochemical techniques.
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We collaborate with the Conrad lab (Microbiology & Molecular Genetics) in identifying mechanisms and alternative therapeutic strategies for endocrine resistant breast cancer. In collaboration with the Neubig lab in Pharmacology & Toxicology, we are exploring appropriate combination therapies in drug-resistant melanoma.
